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BGC0002688NRPS

Benarthin;Dibenarthin

Producing organism
Planobispora rosea
Taxonomy
BacteriaActinomycetotaActinomycetesStreptosporangialesStreptosporangiaceaePlanobispora
Biosynthetic class
NRPS (Type I)
Total steps
6
DOI
MIBiG entry
View on MIBiG ↗

Gene Cluster Map13 genes · 19,983 bp

ACACATE5 kb20.0 kb visible · 19,983 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
ACPAcyl carrier (ACP)
TEThioesterase (TE)

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1
?
+2,3-dihydroxybenz…
Step 2
EV45_RS28710
+L-Arginine
Step 3
EV45_RS28710
+L-Threonine
Step 4TE
EV45_RS28710
Step 5
EV45_RS28710
Step 6TE
EV45_RS28710
Starting stepIntermediateFinal productModuleLoadingTENo modulePKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12688-1?
2,3-dihydroxybenzoate
OC1=C(O)C(C(O)=O)=CC=C1
22688-2EV45_RS28710
2688-1;L-Arginine
from: 2688-1
OC1=C(O)C(C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=CC=C1
32688-3EV45_RS28710
2688-2;L-Threonine
from: 2688-2
OC1=C(O)C(C(N[C@H](C(N[C@H](C(O)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)=CC=C1
42688(1)EV45_RS28710TE
2688-3
from: 2688-3
OC1=C(O)C(C(N[C@H](C(N[C@H](C(O)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)=CC=C1
52688-4EV45_RS28710
2688-3;2688-3
from: 2688-3, 2688-3
C[C@@H](O)[C@H](NC([C@@H](NC(C1=C(O)C(O)=CC=C1)=O)CCC/N=C(N)/N)=O)C(O[C@@H]([C@H](NC([C@@H](NC(C2=C(O)C(O)=CC=C2)=O)CCC/N=C(N)\N)=O)C(O)=O)C)=O
62688(2)EV45_RS28710TE
2688-4
from: 2688-4
C[C@@H](O)[C@H](NC([C@@H](NC(C1=C(O)C(O)=CC=C1)=O)CCC/N=C(N)/N)=O)C(O[C@@H]([C@H](NC([C@@H](NC(C2=C(O)C(O)=CC=C2)=O)CCC/N=C(N)\N)=O)C(O)=O)C)=O
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture