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BGC0002536NRPS

Alazopeptin

Producing organism
Kitasatospora azatica KCTC 9699
Taxonomy
BacteriaActinomycetotaActinomycetesKitasatosporalesStreptomycetaceaeKitasatospora
Biosynthetic class
NRPS (Type I)
Total steps
12
DOI
MIBiG entry
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alazopeptin

Gene Cluster Map20 genes · 27,195 bp

KRKRAAmT5 kb27.2 kb visible · 27,195 bp total
Biosynthetic (additional)
Transport
Unknown
Domains
KRKetoreductase (KR)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
AmTAminotransferase I/II

Pathway Graphsteps arranged in biosynthetic order

12 steps · 11 edges
Step 1
Start
+L-Lysine
Step 4
Start
+L-Aspartic acid
Step 2
BR98_RS33620
Step 5
BR98_RS33685
Step 3
BR98_RS33625
Step 6
?
Step 7
BR98_RS33615
Step 8
BR98_RS33630
+Acetyl-CoA
Step 9
BR98_RS33645;BR98_RS336…
Step 10
BR98_RS33640
Step 11
BR98_RS33610
+(2536-10/2536-7)
Step 12
BR98_RS33660
+L-Alanine
Starting stepIntermediateFinal productModuleLoadingTENo modulePKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions12 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12536-1Start
L-Lysine
N[C@@H](CCCCN)C(O)=O
22536-2BR98_RS33620
2536-1
from: 2536-1
N[C@@H](CCC(O)CN)C(O)=O
32536-3BR98_RS33625
2536-2
from: 2536-2
N[C@@H](CCC(CN)=O)C(O)=O
42536-4Start
L-Aspartic acid
N[C@H](C(O)=O)CC(O)=O
52536-5BR98_RS33685
2536-4
from: 2536-4
O=C(O)CC(C(O)=O)[N+]([O-])=O
62536-6?
2536-5
from: 2536-5
[O-]N=O
72536-7BR98_RS33615
2536-3;2536-6
from: 2536-3, 2536-6
N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O
82536-8BR98_RS33630
2536-7;Acetyl-CoA
from: 2536-7
O=C(O)[C@H](CCC(C=[N+]=[N-])=O)NC(C)=O
92536-9BR98_RS33645;BR98_RS33650
2536-8
from: 2536-8
O=C(O)[C@H](CCC(C=[N+]=[N-])=O)NC(C)=O
102536-10BR98_RS33640
2536-9
from: 2536-9
N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O
112536-11BR98_RS33610
2536-10;(2536-10/2536-7)
from: 2536-10
O=C(O)[C@H](CCC(C=[N+]=[N-])=O)NC([C@H](CCC(C=[N+]=[N-])=O)N)=O
122536BR98_RS33660
2536-11;L-Alanine
from: 2536-11
O=C(O)[C@H](CCC(C=[N+]=[N-])=O)NC([C@H](CCC(C=[N+]=[N-])=O)NC([C@H](C)N)=O)=O
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture