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BGC0002499Hybrid

Enteromycin

Producing organism
Streptomyces achromogenes subsp. streptozoticus
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
PKS (Unknown);NRPS (Type I)
Total steps
8
DOI
MIBiG entry
View on MIBiG ↗
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enteromycin

Gene Cluster Map24 genes · 24,026 bp

TE5 kb24.0 kb visible · 24,026 bp total
Biosynthetic (additional)
Transport
Unknown
Domains
ACPAcyl carrier (ACP)
TEThioesterase (TE)
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

8 steps · 7 edges
Step 1
Start
+Glycine
Step 4
Start
+Asparagine
Step 2
?, etmD
Step 5
?, etmI
Step 3
?
Step 6
etmF
Step 7
etmK, etmQ, etmT
Step 8
etmK, etmQ, etmT
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions8 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12499-1Start—
Glycine
O=C(CN)O—
22499-2?, etmD—
2499-1
from: 2499-1
O=C(/C=N/O)O—
32499-3?—
2499-2
from: 2499-2
O=C(/C=[N+]([O-])/OC)O—
42499-4Start—
Asparagine
N[C@@H](CC(O)=O)C(O)=O—
52499-5?, etmI—
2499-4
from: 2499-4
O=C(O)CCN—
62499-6etmF—
2499-3;2499-5
from: 2499-3, 2499-5
OC(CCNC(/C=[N+](OC)\[O-])=O)=O—
72499-7etmK, etmQ, etmT—
2499-6
from: 2499-6
NC(/C=C/NC(/C=[N+](OC)\[O-])=O)=O—
82499etmK, etmQ, etmT—
2499-6
from: 2499-6
OC(/C=C/NC(/C=[N+](OC)\[O-])=O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture