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BGC0002467NRPS

Thermochelin

Producing organism
Thermocrispum agreste DSM 44070
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Pseudonocardiales›Pseudonocardiaceae›Thermocrispum
Biosynthetic class
NRPS (Type I)
Total steps
5
DOI
MIBiG entry
View on MIBiG ↗

Gene Cluster Map13 genes · 30,976 bp

ACAECAECACAC5 kb31.0 kb visible · 30,976 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
EEpimerization (E)
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

5 steps · 4 edges
Step 1M1
YWY_RS21605
+N-acetyl-δ-N-hydr…
Step 2M2
YWY_RS21605
+Glutamine
Step 3M3
YWY_RS21605
+N-acetyl-δ-N-hydr…
Step 4M4
YWY_RS21605
+Ornithine
Step 5
?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions5 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12467-1YWY_RS21605M1
N-acetyl-δ-N-hydroxyornithine
O=C(C)NC(C(O)=O)CCCN(C(C)=O)O—
22467-2YWY_RS21605M2
2467-1;Glutamine
from: 2467-1
O=C(C)NC(C(NC(C(O)=O)CCC(N)=O)=O)CCCN(C(C)=O)O—
32467-3YWY_RS21605M3
2467-2;N-acetyl-δ-N-hydroxyornithine
from: 2467-2
O=C(C)NC(C(NC(C(N(CCCC(C(O)=O)NC(C)=O)O)=O)CCC(N)=O)=O)CCCN(C(C)=O)O—
42467-4YWY_RS21605M4
2467-3;Ornithine
from: 2467-3
O=C(C)NC(C(NC(C(N(CCCC1NC(C(CCCN(C(O)=O)O)NC1=O)=O)O)=O)CCC(N)=O)=O)CCCN(C(C)=O)O—
52467?—
2467-4
from: 2467-4
O=C(C)NC(C(NC(C(N1O2)=O3)CCC(N)=O)=O)CCCN4O[Me]325(ON(C(C)=O5)CCCC(NC6=O)C(NC6CCC1)=O)O=C4C—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture