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BGC0002365PKS

10-epi-HSAF

Producing organism
Streptomyces sp
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
other (other);PKS (Unknown)
Total steps
8
DOI
MIBiG entry
View on MIBiG ↗
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Gene Cluster Map6 genes · 17,258 bp

KSATDHKRACPCATEER2 kb17.3 kb visible · 17,258 bp total
Biosynthetic (core)
Biosynthetic (additional)
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
EREnoylreductase (ER)
KRKetoreductase (KR)
ACPAcyl carrier (ACP)
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
TEThioesterase (TE)

Pathway Graphsteps arranged in biosynthetic order

8 steps · 7 edges
Step 1
QGU18619.1
Iterative
Step 3
QGU18619.1
Iterative
Step 2
QGU18619.1
+Ornithine
Step 4
QGU18619.1
Step 5
QGU18621.1
Step 6
QGU18620.1
Step 7
QGU18622.1
Step 8
QGU18618.1
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions8 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12365-1QGU18619.1—
OC(/C=C/C=C/C=C/C=C/C=C/C(O)=O)=O{'Iteration': [(['None'], 'M…
22365-2QGU18619.1—
2365-1;Ornithine
from: 2365-1
OC(/C=C/C=C/C=C/C=C/C=C/C(NCCCC(C(O)=O)N)=O)=O—
32365-3QGU18619.1—
OC(/C=C/C=C/C=C/C=C/C(CC(O)=O)=O)=O{'Iteration': [(['None'], 'M…
42365-4QGU18619.1—
2365-2;2365-3
from: 2365-2, 2365-3
C/C=C/C=C/C=C/C=C/C=C/C(NCCCC1NC(C(C(/C=C/C=C/C=C/C=C/C)=O)=C1O)=O)=O—
52365-5QGU18621.1—
2365-4
from: 2365-4
CC[C@@H]1C[C@@](/C=C/C=C/C=C/C(NCCC[C@]2([H])NC3=O)=O)([H])[C@@](/C=C/C=C/C=C/C(O)=C3\C2=O)([H])[C@H]1C—
62365-6QGU18620.1—
2365-5
from: 2365-5
CC[C@@H]1C[C@@]2([H])[C@@]([C@]([C@](/C=C/C=C/C(NCCC[C@]3([H])NC4=O)=O)([H])C2)([H])[C@@H](O)/C=C/C=C/C(O)=C4\C3=O)([H])[C@H]1C—
72365-7QGU18622.1—
2365-6
from: 2365-6
CC[C@@H]1C[C@@]2([H])[C@@]([C@]3([H])[C@@H](O)[C@@H]4C[C@H](C/C=C/C(NCCC[C@@]5([H])C(/C(C(N5)=O)=C(\C=C\4)O)=O)=O)[C@@]3([H])C2)([H])[C@H]1C—
82365QGU18618.1—
2365-7
from: 2365-7
CC[C@@H]1C[C@@]2([H])[C@@]([C@]3([H])[C@@H](O)[C@@H]4C[C@H](C/C=C/C(NCC[C@H](O)[C@@]5([H])C(/C(C(N5)=O)=C(\C=C\4)O)=O)=O)[C@@]3([H])C2)([H])[C@H]1C—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture