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BGC0002359NRPS

dudomycin A

Producing organism
Streptomyces albus subsp. chlorinus
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type 1)
Total steps
6
DOI
MIBiG entry
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dudomycin A

Gene Cluster Map23 genes · 27,968 bp

CATE5 kb28.0 kb visible · 27,968 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
TEThioesterase (TE)
MTMethyltransferase

Pathway Graphsteps arranged in biosynthetic order

6 steps · 6 edges
Step 1
Start
+Valine
Step 2
?
Step 3
?
Step 4
?
+malonyl-CoA, malonyl-CoA
Step 5
FM076_21195
+Lysine
Step 6TE
FM076_21195
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12359-1Start—
Valine
CC(C)C(N)C(O)=O—
22359-2?—
2359-1
from: 2359-1
CC(C)C(C(O)=O)=O—
32359-3?—
2359-2
from: 2359-2
OC(C(C)C)=O—
42359-4?—
2359-2;malonyl-CoA;malonyl-CoA
from: 2359-2
O=C(O)CC(CCC(C)C)O—
52359-5FM076_21195—
2359-3;2359-3;Lysine
from: 2359-3, 2359-3
CC(C)CCC(O)CC(NCCCCC(C(O)=O)NC(CC(CCC(C)C)O)=O)=O—
62359FM076_21195TE
2359-4;2359-3
from: 2359-4, 2359-3
CC(C)CCC(O)CC(NCCCCC(C(O)=O)NC(CC(CCC(C)C)OC(CC(O)CCC(C)C)=O)=O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture