NPdia

BGC0002358PKS

cyclofaulknamycin

Producing organism: Streptomyces albidoflavus
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces›Streptomyces albidoflavus group
Biosynthetic class: PKS (Unknown)
Total steps: 7
DOI: 10.3390/microorganisms9081609
MIBiG entry: View on MIBiG ↗

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cyclofaulknamycin

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Unknown

Domains

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Thioesterase (TE)

Epimerization (E)

TauD oxygenase

TIGR01720

7 steps · 6 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions7 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`2358-1`	XNR_0983	M1	Phenylalanine	`OC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O`	—
2	`2358-2`	XNR_0983	M2	2358-1;Leucine from: 2358-1	`CC(C)C[C@@H](NC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O)C(O)=O`	—
3	`2358-3`	XNR_0983	M3	2358-2;Valine from: 2358-2	`O=C([C@@H](NC([C@H](NC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O)CC(C)C)=O)C(C)C)O`	—
4	`2358-4`	XNR_0985	M4	2358-3;Arginine from: 2358-3	`OC([C@H](NC([C@@H](NC([C@H](NC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O)CC(C)C)=O)C(C)C)=O)[C@H]2NC(NCC2)=N)=O`	—
5	`2358-5`	XNR_0985	M5	2358-4;Threonine from: 2358-4	`OC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O)CC(C)C)=O)C(C)C)=O)[C@H]2NC(NCC2)=N)=O)[C@@H](C)O)=O`	—
6	`2358-6`	XNR_0985	M6	2358-5;Threonine from: 2358-5	`O[C@H](C)[C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](N)[C@@H](C1=CC=CC=C1)O)=O)CC(C)C)=O)C(C)C)=O)[C@H]2NC(NCC2)=N)=O)[C@@H](C)O)=O)C(O)=O`	—
7	`2358`	XNR_0982	—	2358-6 from: 2358-6	`O=C([C@@H](NC([C@H](NC([C@@H](NC([C@H]1[C@@H](C)O)=O)[C@H](O)C2=CC=CC=C2)=O)CC(C)C)=O)C(C)C)N[C@@H](C(N[C@H](C(N1)=O)[C@H](O)C)=O)[C@@H](N3)CCNC3=N`	—

Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture