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BGC0002340NRPS

pyrroloformamide A;pyrroloformamide B;pyrroloformamide C;pyrroloformamide D

Producing organism
Streptomyces sp. CB02980
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type 1);other (other)
Total steps
9
DOI
MIBiG entry
View on MIBiG ↗
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Gene Cluster Map24 genes · 28,112 bp

TECyATEC5 kb28.1 kb visible · 28,112 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Other
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
TEThioesterase (TE)
CyHeterocyclization (Cy)
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

9 steps · 8 edges
Step 1
start
Step 2
E0F75_025360
Step 3
?
Step 4
?
Step 5
E0F75_025300
Step 6
?
Step 7
E0F75_025400
+2340(1)
Step 8
?
+2340(2)
Step 9
?
+2340(2)
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions9 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12340-1start—
N[C@H](S)C(O)=O—
22340-2E0F75_025360—
2340-1;2340-1
from: 2340-1, 2340-1
O=C(O)[C@@H](S)NC(O)[C@@H](S)N—
32340-3?—
2340-2
from: 2340-2
O=C1C(N)=C(S)C(CS)(C(O)=O)N1—
42340-4?—
2340-3
from: 2340-3
O=C1C(N)=C(S)/C(N1)=C\S—
52340-5E0F75_025300—
2340-4
from: 2340-4
O=C1C(N)=C2C(N1)=CSS2—
62340(1)?—
2340-5
from: 2340-5
O=C1C(NC([H])=O)=C2C(N1)=CSS2—
72340(2)E0F75_025400—
2340(1)
O=C1C(N(C)C([H])=O)=C2C(N1)=CSS2—
82340(3)?—
2340(2)
O=C1C(N(C)C([H])=O)=C2C(N1)=CSCS2—
92340(4)?—
2340(2)
O=C1C(N(C)C([H])=O)=C2C(N1)=CSS2(=O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture