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BGC0002295NRPS

minimycin;indigodine

Producing organism
Streptomyces hygroscopicus
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces›Streptomyces violaceusniger group
Biosynthetic class
NRPS (Type 1);saccharide (None)
Total steps
8
DOI
MIBiG entry
View on MIBiG ↗
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Gene Cluster Map5 genes · 9,315 bp

APCPTE2 kb9.3 kb visible · 9,315 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Unknown
Domains
AAdenylation (A)
PCPPeptidyl carrier (PCP)
TEThioesterase (TE)

Pathway Graphsteps arranged in biosynthetic order

8 steps · 7 edges
Step 1M1
Start
+L-Glutamine
Step 2
minA
Step 3TE
minA
Step 4
minA
Step 8
?
Step 5
minB
Step 6
minC
Step 7
minC
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions8 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12295-1StartM1
L-Glutamine
O=C(O)[C@H](CCC(N)=O)N—
22295-2minA—
2295-1
from: 2295-1
O=C(O)/C(N)=C/CC(N)=O—
32295-3minATE
2295-2
from: 2295-2
NC1=CCC(NC1=O)=O—
42295-4minA—
2295-3
from: 2295-3
NC1C=CC(NC1=O)=O—
52295-5minB—
2295-4
from: 2295-4
NC1C=C([C@H]2[C@H](O)[C@H](O)[C@@H](CO[P])O2)C(NC1=O)=O—
62295-6minC—
2295-5
from: 2295-5
O=C(OC=C1[C@H]2[C@H](O)[C@H](O)[C@@H](CO[P])O2)NC1=O—
72295(1)minC—
2295-6
from: 2295-6
O=C(OC=C1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)NC1=O—
82295(2)?—
2295-3;2295-3
from: 2295-3, 2295-3
NC1=C/C(C(NC1=O)=O)=C2C(NC(C(N)=C\2)=O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture