NPdia

BGC0002147NRPS

behemamine A;behemamine B;behemamine C

Producing organism: Streptomyces sp. CB02009
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: NRPS (Type 1)
Total steps: 11
DOI: 10.1021/acs.orglett.0c01224
MIBiG entry: View on MIBiG ↗

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Other

Unknown

Domains

Ketoreductase (KR)

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Thioesterase (TE)

11 steps · 10 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions11 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`2147-1`	Start	—	L-Leucine	`NC(C(O)=O)CC(C)C`	—
2	`2147-2`	AMK27_13920,AMK27_13925,AMK27_13930	—	2147-1 from: 2147-1	`CC(C)CC([R])=O`	—
3	`2147-3`	AMK27_13935	—	2147-2 from: 2147-2	`C/C(C)=C\C([R])=O`	—
4	`2147-4`	AMK27_13910	M1	2147-3;Serine from: 2147-3	`C/C(C)=C\C(N[C@@H](CO)C(O)=O)=O`	—
5	`2147-5`	AMK27_13910	M2	2147-4;5-MethylProline from: 2147-4	`C/C(C)=C\C(N[C@@H](CO)C(N1[C@H](C(O)=O)CC[C@@H]1C)=O)=O`	—
6	`2147-6`	AMK27_13910	TE	2147-5 from: 2147-5	`C/C(C)=C\C(NC(C1=O)=CC(C2N1[C@@H](C)CC2)=O)=O`	—
7	`2147-7`	AMK27_13915	—	2147-6 from: 2147-6	`C/C(C)=C\C(NC(N1C2CC[C@@H]1C)=CC2=O)=O`	—
8	`2147-8`	AMK27_13895	—	2147-7 from: 2147-7	`C/C(C)=C\C(NC(N1[C@@]2(C)CC[C@@H]1C)=CC2=O)=O`	—
9	`2147-9`	OKJ62367.1	—	2147-8 from: 2147-8	`C/C(C)=C\C(NC(N1[C@@]2(C)[C@H](O3)[C@H]3[C@@H]1C)=CC2=O)=O`	—
10	`2147-10`	OKJ62367.1	—	2147-8 from: 2147-8	`C/C(C)=C\C(NC(N1[C@@]2(C)C([H])[C@H](O)[C@@H]1C)=CC2=O)=O`	—
11	`2147-11`	OKJ62367.1	—	2147-8 from: 2147-8	`C/C(C)=C\C(NC(N1[C@@]2(C)[C@H](O)C([H])[C@@H]1C)=CC2=O)=O`	—

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