NPdia

BGC0002138PKS

fuelimycin A;fuelimycin B;fuelimycin C

Producing organism: Streptomyces albireticuli
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: PKS (iterative type 1)
Total steps: 8
DOI: 10.1016/j.joule.2022.05.011
MIBiG entry: View on MIBiG ↗

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C₂₉H₃₈O₂418.29 Da

Biosynthetic (core)

Biosynthetic (additional)

Unknown

Domains

Ketosynthase (KS)

Acyltransferase (AT)

Dehydratase (DH)

Ketoreductase (KR)

Acyl carrier (ACP)

8 steps · 7 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions8 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`2138-1`	CK936_29005	—	Acetyl-CoA;Malonyl-CoA	`OC(CC(C)=O)=O`	—
2	`2138-2`	CK936_29005;CK936_29015	—	2138-1 from: 2138-1	`OC(/C=C/C)=O`	—
3	`2138-3`	CK936_29010	—	2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2 from: 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2	`CC1C(C1)C(C2)C2C3C(C3)C(C4)C4C5C(C5)C(C6)C6C7C(C7)/C=C/C=C/C=C/C(O)=O`	—
4	`2138(1)`	CK936_29020	TE	2138-3 from: 2138-3	`CC1C(C1)C(C2)C2C3C(C3)C(C4)C4C5C(C5)C(C6)C6C7C(C7)/C=C/C=C/C=C/C(O)=O`	—
5	`2138-4`	CK936_29010	—	2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2 from: 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2	`CC1C(C1)C(C2)C2C3C(C3)C(C4)C4C5C(C5)C(C6)C6C7C(C7)/C=C/C=C/C(O)=O`	—
6	`2138(2)`	CK936_29020	TE	2138-4 from: 2138-4	`CC1C(C1)C(C2)C2C3C(C3)C(C4)C4C5C(C5)C(C6)C6C7C(C7)/C=C/C=C/C(O)=O`	—
7	`2138-5`	CK936_29010	—	2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2;2138-2 from: 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2, 2138-2	`CC(C1)C1C2C(C2)C(C3)C3C4C(C4)C(C5)C5C6C(C6)/C=C/C=C/C=C/C(O)=O`	—
8	`2138(3)`	CK936_29020	TE	2138-5 from: 2138-5	`CC(C1)C1C2C(C2)C(C3)C3C4C(C4)C(C5)C5C6C(C6)/C=C/C=C/C=C/C(O)=O`	—

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