NPdia
← Back to Repository
BGC0002106PKS

rimocidin

Producing organism
Streptomyces rimosus subsp. rimosus
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
PKS (Modular type 1)
Total steps
17
DOI
MIBiG entry
View on MIBiG ↗
Loading…
rimocidin

Gene Cluster Map22 genes · 96,694 bp

20 kb96.7 kb visible · 96,694 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Other
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
KRKetoreductase (KR)
ACPAcyl carrier protein (ACP)
ACPAcyl carrier (ACP)
AAdenylation (A)
TEThioesterase (TE)
DnDocking N-term
DcDocking C-term

Pathway Graphsteps arranged in biosynthetic order

17 steps · 16 edges
Step 1Load
IH19_RS0119170
+Ethylmalonyl-CoA
Step 16
Start
+Mycosamine
Step 2M1
IH19_RS0119135
+malonyl-CoA
Step 3M2
IH19_RS0119135
+malonyl-CoA
Step 4M3
IH19_RS0119135
+malonyl-CoA
Step 5M4
IH19_RS0119135
+malonyl-CoA
Step 6M5
IH19_RS0119115
+malonyl-CoA
Step 7M6
IH19_RS0119115
+malonyl-CoA
Step 8M7
IH19_RS0119115
+methylmalonyl-CoA
Step 9M8
?
+malonyl-CoA
Step 10M9
?
+malonyl-CoA
Step 11M10
?
+malonyl-CoA
Step 12M11
?
+malonyl-CoA
Step 13M12
?
+malonyl-CoA
Step 14M13
?
+ethylmalonyl-CoA
Step 15TE
IH19_RS0119090/IH19_RS1…
Step 17
?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions17 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12106-1IH19_RS0119170Loading
Ethylmalonyl-CoA
OC(CCC)=O—
22106-2IH19_RS0119135M1
2106-1;malonyl-CoA
from: 2106-1
OC(CCC)CC(O)=O—
32106-3IH19_RS0119135M2
2106-2;malonyl-CoA
from: 2106-2
OC(CCC)C/C=C/C(O)=O—
42106-4IH19_RS0119135M3
2106-3;malonyl-CoA
from: 2106-3
OC(CCC)C/C=C/C=C/C(O)=O—
52106-5IH19_RS0119135M4
2106-4;malonyl-CoA
from: 2106-4
OC(CCC)C/C=C/C=C/C=C/C(O)=O—
62106-6IH19_RS0119115M5
2106-5;malonyl-CoA
from: 2106-5
OC(/C=C/C=C/C=C/C=C/CC(O)CCC)=O—
72106-7IH19_RS0119115M6
2106-6;malonyl-CoA
from: 2106-6
OC(CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O—
82106-8IH19_RS0119115M7
2106-7;methylmalonyl-CoA
from: 2106-7
OC(C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O—
92106-9?M8
2106-8;malonyl-CoA
from: 2106-8
OC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O—
102106-10?M9
2106-9;malonyl-CoA
from: 2106-9
OC(CC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O)=O—
112106-11?M10
2106-10;malonyl-CoA
from: 2106-10
OC(CC(O)CC(CC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O)=O)=O—
122106-12?M11
2106-11;malonyl-CoA
from: 2106-11
OC(CCCC(O)CC(CC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O)=O)=O—
132106-13?M12
2106-12;malonyl-CoA
from: 2106-12
OC(CC(CCCC(O)CC(CC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O)=O)=O)=O—
142106-14?M13
2106-13;ethylmalonyl-CoA
from: 2106-13
O=C(O)C(C(O)CC(CCCC(O)CC(CC(CC(O)C(C)C(O)CC(O)/C=C/C=C/C=C/C=C/CC(O)CCC)=O)=O)=O)CC—
152106-15IH19_RS0119090/IH19_RS1000000150160TE
2106-14
from: 2106-14
OC(CCCC(CC(C(CC)C(OC(CCC)C/C=C/C=C/C=C/C=C/C(O)C1)=O)O)=O)CC2(O)OC1C(C)C(O)C2—
162106-16Start—
Mycosamine
O[C@H]1[C@H](O)[C@H](N)[C@@H](O)[C@@H](C)O1—
172106?—
2106-15;2106-16
from: 2106-15, 2106-16
OC(CCCC(CC(C(CC)C(OC(CCC)C/C=C/C=C/C=C/C=C/C(O[C@H]1[C@H](O)[C@H](N)[C@@H](O)[C@@H](C)O1)C2)=O)O)=O)CC3(O)OC2C(C(O)=O)C(O)C3—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture