NPdia
← Back to Repository
BGC0002096PKS

tetrachlorizine

Producing organism
Streptomyces sp. AJS327
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
PKS (Unknown)
Total steps
5
DOI
MIBiG entry
View on MIBiG ↗
Loading…
tetrachlorizine

Gene Cluster Map22 genes · 35,401 bp

TEAKSKSATTDKSATKSATKR5 kb35.4 kb visible · 35,401 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
KRKetoreductase (KR)
ACPAcyl carrier protein (ACP)
ACPAcyl carrier (ACP)
AAdenylation (A)
ACPAcyl carrier (ACP)
TEThioesterase (TE)
TDTerminal reductase
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

5 steps · 4 edges
Step 1
Start
+L-Proline
Step 2
E0L36_23610,E0L36_23555…
Step 3
E0L36_23620,E0L36_23615…
Step 4
E0L36_23600
Step 5
E0L36_23590
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions5 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12096-1Start—
L-Proline
O=C(O)[C@@]1([H])NCCC1—
22096-2E0L36_23610,E0L36_23555,E0L36_23550—
2096-1
from: 2096-1
O=C(O)C1=CC(Cl)=C(Cl)N1—
32096-3E0L36_23620,E0L36_23615,E0L36_23605,E0L36_23585,E0L36_23580—
2096-2
from: 2096-2
O=C(CC(C(C(CC(O)=O)=O)CCC(C1=CC(Cl)=C(Cl)N1)=O)=O)C2=CC(Cl)=C(Cl)N2—
42096-4E0L36_23600—
2096-3
from: 2096-3
OC1=CC=C(C(C2=CC(Cl)=C(Cl)N2)=O)C(O)=C1CCC(C3=CC(Cl)=C(Cl)N3)=O—
52096-5E0L36_23590—
2096-4
from: 2096-4
OC1=CC=C(C(C2=CC(Cl)=C(Cl)N2)=O)C(O)=C1/C=C/C(C3=CC(Cl)=C(Cl)N3)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture