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BGC0002051NRPS

antipain

Producing organism
Streptomyces sp
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type 1)
Total steps
6
DOI
MIBiG entry
View on MIBiG ↗
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antipain

Gene Cluster Map6 genes · 13,500 bp

CCAPCPAPCPAPCPC2 kb13.5 kb visible · 13,500 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1
NAI38-463
+Phenylalanine
Step 2
NAI38-463
+Acetyl-CoA
Step 3
NAI38-462
+Arginine
Step 4
NAI38-461;NAI38-464
+Valine
Step 5
NAI38-462
Iterative
Step 6
NAI38-465,?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12051-1NAI38-463—
Phenylalanine
OC([C@@H](N)CC1=CC=CC=C1)=O—
22051-2NAI38-463—
2051-1;Acetyl-CoA
from: 2051-1
OC([C@@H](NC(O)=O)CC1=CC=CC=C1)=O—
32051-3NAI38-462—
2051-2;Arginine
from: 2051-2
OC([C@@H](NC(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC1=CC=CC=C1)=O—
42051-4NAI38-461;NAI38-464—
2051-3;Valine
from: 2051-3
OC([C@@H](NC(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCCNC(N)=N)=O)CC1=CC=CC=C1)=O—
52051-5NAI38-462—
2051-4
from: 2051-4
OC([C@@H](NC(N[C@H](C(N[C@@H](C(C)C)C(NC(C([H])=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CC1=CC=CC=C1)=O{'Iteration': [((NAI38-462),…
62051NAI38-465,?—
2051-5
from: 2051-5
OC([C@@H](NC(N[C@H](C(N[C@@H](C(C)C)C(NC(C([H])=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CC1=CC=CC=C1)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture