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BGC0002042NRPS

anthelvencin A;anthelvencin B;anthelvencin C

Producing organism
Streptomyces venezuelae
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type 1)
Total steps
9
DOI
MIBiG entry
View on MIBiG ↗
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C19H25N9O3427.21 Da

Gene Cluster Map22 genes · 26,113 bp

ACAmTCER5 kb26.1 kb visible · 26,113 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
EREnoylreductase (ER)
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
AmTAminotransferase I/II
NADNAD-binding

Pathway Graphsteps arranged in biosynthetic order

9 steps · 9 edges
Step 1
start
+Glutamine
Step 3
start
+4-acetamidopyrrol…
Step 2
ant24
Step 4
ant19;ant22
Step 5
ant14,ant19,ant22,ant23
Step 6
ant14,ant16
Step 7
ant24
+3-aminopropionami…
Step 8
ant15
+2042(1)
Step 9
ant15
+2042(2)
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions9 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12042-1start—
Glutamine
NC(CCC(N)C(O)=O)=O—
22042-2ant24—
2042-1
from: 2042-1
NC1=NC(C(O)=O)CC1—
32042-3start—
4-acetamidopyrrole-2-carboxylate
O=C(C1=CC(NC(C)=O)=CN1)O—
42042-4ant19;ant22—
2042-3
from: 2042-3
OC(C1=CC(NC(C)=O)=CN1)=O—
52042-5ant14,ant19,ant22,ant23—
2042-2;2042-4
from: 2042-2, 2042-4
NC1=NC(C(NC2=CNC(C(O)=O)=C2)=O)CC1—
62042-6ant14,ant16—
2042-4;2042-5
from: 2042-4, 2042-5
NC1=NC(C(NC2=CNC(C(NC3=CNC(C(O)=O)=C3)=O)=C2)=O)CC1—
72042(1)ant24—
2042-6;3-aminopropionamidine
from: 2042-6
NC1=NC(C(NC2=CNC(C(NC3=CNC(C(NCCC(N)=N)=O)=C3)=O)=C2)=O)CC1—
82042(2)ant15—
2042(1)
NC1=NC(C(NC2=CN(C)C(C(NC3=CNC(C(NCCC(N)=N)=O)=C3)=O)=C2)=O)CC1—
92042(3)ant15—
2042(2)
NC1=NC(C(NC2=CN(C)C(C(NC3=CN(C)C(C(NCCC(N)=N)=O)=C3)=O)=C2)=O)CC1—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture