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BGC0002017NRPS

potensibactin

Producing organism
Nocardiopsis potens DSM 45234
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Streptosporangiales›Nocardiopsaceae›Nocardiopsis
Biosynthetic class
NRPS(Type1)
Total steps
7
DOI
MIBiG entry
View on MIBiG ↗
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potensibactin
C29H42N8O14726.28 Da

Gene Cluster Map5 genes · 12,514 bp

AACPCAPCPCAPCPC2 kb12.5 kb visible · 12,514 bp total
Biosynthetic (core)
Biosynthetic (additional)
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
ACPAcyl carrier (ACP)

Pathway Graphsteps arranged in biosynthetic order

7 steps · 6 edges
Step 1Load
ctg4_3
+2,3-Dihydroxybenz…
Step 2M1
ctg4_5
+Glycine
Step 3M2
ctg4_5
+Glycine
Step 4M3
?
+Serine
Step 5M4
?
+Serine
Step 6M5
?
+N-OH-N-Acetyl-Orn…
Step 7M6
?
+Cyclic-N-OH-Ornit…
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions7 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
12017-1ctg4_3Loading
2,3-Dihydroxybenzoic acid
OC(C1=CC=CC(O)=C1O)=O—
22017-2ctg4_5M1
2017-1;Glycine
from: 2017-1
O=C(N)CNC(C1=CC=CC(O)=C1O)=O—
32017-3ctg4_5M2
2017-2;Glycine
from: 2017-2
O=C(NCC(N)=O)CNC(C1=CC=CC(O)=C1O)=O—
42017-4?M3
2017-3;Serine
from: 2017-3
O=C(NCC(NC(CO)C(N)=O)=O)CNC(C1=CC=CC(O)=C1O)=O—
52017-5?M4
2017-4;Serine
from: 2017-4
O=C(NCC(NC(CO)C(NC(C(N)=O)CO)=O)=O)CNC(C1=CC=CC(O)=C1O)=O—
62017-6?M5
2017-5;N-OH-N-Acetyl-Ornithine
from: 2017-5
O=C(NCC(NC(CO)C(NC(C(NC(CCCN(C(C)=O)O)C(NC1CCCN(O)C1=O)=O)=O)CO)=O)=O)CNC(C2=CC=CC(O)=C2O)=O—
72017?M6
2017-6;Cyclic-N-OH-Ornithine
from: 2017-6
O=C(NCC(NC(CO)C(NC(C(NC(CCCN(C(C)=O)O)C(NC1CCCN(O)C1=O)=O)=O)CO)=O)=O)CNC(C2=CC=CC(O)=C2O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture