NPdia
← Back to Repository
BGC0001942Hybrid

Malonomycin

Producing organism
Streptomyces paromomycinus
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I);PKS (Unknown)
Total steps
6
DOI
MIBiG entry
View on MIBiG ↗
Loading…
malonomycin
C13H18N4O9374.11 Da

Gene Cluster Map18 genes · 35,061 bp

AACTECACAKSCAC5 kb35.1 kb visible · 35,061 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Unknown
Domains
KSKetosynthase (KS)
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
ACPAcyl carrier (ACP)
TEThioesterase (TE)

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1M1
mloI
+L-Serine
Step 2M2
mloI
+L-Asparagine
Step 3M3
mloJ
+Malonyl-CoA
{'Missing':['AT']
Step 4M4
mloJ
+L-Diaminopropiona…
Step 5TE
mloC
Step 6
mloH
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11942-1mloIM1
L-Serine
OC([C@H](CO)N)=O—
21942-2mloIM2
1942-1;L-Asparagine
from: 1942-1
O=C(N[C@H](C(O)=O)CC(O)=O)[C@H](CO)N—
31942-3mloJM3
1942-2;Malonyl-CoA
from: 1942-2
O=C(N[C@H](C(O)=O)CC(CC(O)=O)=O)[C@H](CO)N{'Missing':['AT']
41942-4mloJM4
1942-3;L-Diaminopropionate
from: 1942-3
O=C(CC(C[C@H](NC([C@@H](N)CO)=O)C(O)=O)=O)N[C@@H](CN)C(O)=O—
51942-5mloCTE
1942-4
from: 1942-4
O=C(C[C@H](NC([C@@H](N)CO)=O)C(O)=O)C1=C(O)[C@H](CN)NC1=O—
61942mloH—
1942-5
from: 1942-5
O=C(CC(NC([C@@H](N)CO)=O)(C(O)=O)C(O)=O)C1=C(O)[C@H](CN)NC1=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture