NPdia

BGC0001846NRPS

Valinomycin;Montanastatin

Producing organism: Streptomyces sp. CBMAI 2042
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: saccharide (hybrid/tailoring);NRPS (Type I)
Total steps: 7
DOI: 10.1002/slct.201900922
MIBiG entry: View on MIBiG ↗

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C₅₄H₉₀N₆O₁₈1110.63 Da

Biosynthetic (core)

Biosynthetic (additional)

Transport

Other

Unknown

Domains

Ketoreductase (KR)

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Acyl carrier (ACP)

Thioesterase (TE)

Epimerization (E)

CoA-ligase (CAL)

7 steps · 6 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`1846-1`	STAN_6722	M1	α-Ketoisovalerate	`O[C@@H](C(O)=O)C(C)C`	—
2	`1846-2`	STAN_6722	M2	1846-1;L-Valine from: 1846-1	`O[C@@H](C(N[C@@H](C(O)=O)C(C)C)=O)C(C)C`	—
3	`1846-3`	STAN_6722;STAN_6721	M3	1846-2;Pyruvate from: 1846-2	`O[C@@H](C(N[C@@H](C(O[C@H](C(O)=O)C)=O)C(C)C)=O)C(C)C`	—
4	`1846-4`	STAN_6721	M4	1846-3;L-Valine from: 1846-3	`O[C@@H](C(N[C@@H](C(O[C@H](C(N[C@H](C(O)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C`	—
5	`1846-5`	STAN_6721	TE	1846-4 from: 1846-4	`O[C@@H](C(N[C@@H](C(O[C@H](C(N[C@H](C(O)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C`	—
6	`1846(1)`	?	—	1846-5;1846-5;1846-5 from: 1846-5, 1846-5, 1846-5	`O=C1[C@H](NC([C@H](OC([C@@H](NC([C@@H](OC([C@H](NC([C@H](OC([C@@H](NC([C@@H](OC([C@H](NC([C@H](OC([C@@H](NC([C@@H](O1)C(C)C)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)C)=O)C(C)C`	—
7	`1846(2)`	?	—	1846-5;1846-5 from: 1846-5, 1846-5	`O=C(N[C@@H](C(C)C)C1=O)[C@H](C)OC([C@@H](C(C)C)CC([C@@H](C(C)C)OC([C@H](C(C)C)NC([C@@H](OC([C@@H](C(C)C)NC([C@H](O1)C(C)C)=O)=O)C)=O)=O)=O)=O`	—

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