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BGC0001810PKS

Trehangelin

Producing organism
Polymorphospora rubra
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Micromonosporales›Micromonosporaceae›Polymorphospora
Biosynthetic class
PKS (Unknown)
Total steps
6
DOI
MIBiG entry
View on MIBiG ↗
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trehangelin
C22H34O13506.20 Da

Gene Cluster Map12 genes · 16,267 bp

ECHKR2 kb16.3 kb visible · 16,267 bp total
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
KRKetoreductase (KR)
ECHEnoyl-CoA hydratase

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1
Start
+Acetyl-CoA
Step 5
thgC, thgD
+Starch
Step 2
thgI
+Methylmalonyl-CoA
Step 3
thgK
Step 4
thgH
Step 6
thgJ
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11810-1Start—
Acetyl-CoA
O=C([R])C—
21810-2thgI—
1810-1;Methylmalonyl-CoA
from: 1810-1
O=C([R])C(C(C)=O)C—
31810-3thgK—
1810-2
from: 1810-2
O=C([R])C(C(O)C)C—
41810-4thgH—
1810-3
from: 1810-3
O=C([R])/C(C)=C\C—
51810-5thgC, thgD—
Starch
O[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)C(O)[C@H](O)[C@H]2O)O[C@@H]1CO—
61810thgJ—
1810-4;1810-5
from: 1810-4, 1810-5
O[C@H]1[C@H](OC(/C(C)=C\C)=O)[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)C(O)[C@H](OC(/C(C)=C\C)=O)[C@H]2O)O[C@@H]1CO—
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