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BGC0001771NRPS

Scleric acid

Producing organism
Streptomyces sclerotialus
Taxonomy
Bacteria›Actinobacteria›Streptomycetales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I)
Total steps
10
DOI
MIBiG entry
View on MIBiG ↗

Gene Cluster Map17 genes · 18,478 bp

CATE5 kb18.5 kb visible · 18,478 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Unknown
Domains
CCondensation (C)
AAdenylation (A)
ACPAcyl carrier (ACP)
TEThioesterase (TE)
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

10 steps · 9 edges
Step 1
Start
Step 5
IG96_RS37880
Step 7
IG96_RS0135535, IG96_RS…
Step 2
IG96_RS0135485, ?
Step 8
IG96_RS0135550
Step 3
IG96_RS0135475
Step 4
IG96_RS0135490
Step 6
?
Step 9
?
Step 10
IG96_RS0135530
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions10 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11771-1Start—
O[C@@H]([C@H](O)COP([O-])([O-])=O)C(CO)=O—
21771-2IG96_RS0135485, ?—
1771-1
from: 1771-1
OC(CO)[Th]([P])[2H]—
31771-3IG96_RS0135475—
1771-2
from: 1771-2
SCCCSC(CO)=O—
41771-4IG96_RS0135490—
1771-3
from: 1771-3
O=C(CO)O—
51771-5IG96_RS37880—
O=C([C@@H]1CCCN1)O—
61771-6?—
1771-4;1771-5
from: 1771-4, 1771-5
O=C([C@@H]1CCCN1C(CO)=O)O—
71771-7IG96_RS0135535, IG96_RS0135540, IG96_RS0135545—
OC(C1=CC=CC=C1)=O—
81771-8IG96_RS0135550—
1771-7
from: 1771-7
O=C(OP([O-])([O-])=O)C1=CC=CC=C1—
91771-9?—
1771-6;1771-8
from: 1771-6, 1771-8
O=C([C@@H]1CCCN1C(COC(C2=CC=CC=C2)=O)=O)O—
101771-10IG96_RS0135530—
1771-9
from: 1771-9
O=C([C@@H]1CCCN1C(COC(C2=CC=CC=C2)=O)=O)O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture