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BGC0001752NRPS

Qinichelins

Producing organism
Streptomyces roseifaciens
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I)
Total steps
15
DOI
MIBiG entry
View on MIBiG ↗

Gene Cluster Map18 genes · 39,092 bp

AmTCAECACAECACACA10 kb39.1 kb visible · 39,092 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Other
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
ACPAcyl carrier (ACP)
CnCOM N-term
EEpimerization (E)
AmTAminotransferase III
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

15 steps · 16 edges
Step 1
Start
Step 8
ctg1_orf1262
+Dihydroxybenzoate
Step 2
ctg1_orf1258
Step 9M1
ctg1_orf1264
+Serine
Step 3
ctg1_orf1259
Step 4
ctg1_orf1256
Step 5
ctg1_orf1260
Step 6
ctg1_orf1258
Step 7
ctg1_orf1259
Step 10M2
ctg1_orf1264
Step 11M3
ctg1_orf1264
+Serine
Step 12M4
ctg1_orf1265
+Serine
Step 13M5
ctg1_orf1265
Step 14M6
ctg1_orf1265
Step 15
?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions15 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11752-1Start—
O=C(CC[C@@H](C(O)=O)N)O—
21752-2ctg1_orf1258—
1752-1
from: 1752-1
O=C(CC[C@@H](C(O)=O)NC(C)=O)O—
31752-3ctg1_orf1259—
1752-2
from: 1752-2
O=C(CC[C@@H](C(O)=O)NC(C)=O)OP([O-])([O-])=O—
41752-4ctg1_orf1256—
1752-3
from: 1752-3
O=C(CC[C@@H](C(O)=O)NC(C)=O)[H]—
51752-5ctg1_orf1260—
1752-4
from: 1752-4
NCCC[C@@H](C(O)=O)NC(C)=O—
61752-6ctg1_orf1258—
1752-5
from: 1752-5
NCCC[C@@H](C(O)=O)N—
71752-7ctg1_orf1259—
1752-6
from: 1752-6
N[C@H](C(O)=O)CCCNO—
81752-8ctg1_orf1262—
Dihydroxybenzoate
OC1=C(O)C(C(O)=O)=CC=C1—
91752-9ctg1_orf1264M1
1752-8;Serine
from: 1752-8
OC1=C(O)C(C(N[C@@H](C(O)=O)CO)=O)=CC=C1—
101752-10ctg1_orf1264M2
1752-9;1752-6
from: 1752-9, 1752-6
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(O)=O)CCCN)=O)CO)=O)=CC=C1—
111752-11ctg1_orf1264M3
1752-10;Serine
from: 1752-10
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(O)=O)=O)CCCN)=O)CO)=O)=CC=C1—
121752-12ctg1_orf1265M4
1752-11;Serine
from: 1752-11
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(N[C@@H](CO)C(O)=O)=O)=O)CCCN)=O)CO)=O)=CC=C1—
131752-13ctg1_orf1265M5
1752-12;1752-7
from: 1752-12, 1752-7
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(N[C@@H](CO)C(N(O)CCC[C@@H](C(O)=O)N)=O)=O)=O)CCCN)=O)CO)=O)=CC=C1—
141752-14ctg1_orf1265M6
1752-13;1752-7
from: 1752-13, 1752-7
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(N[C@@H](CO)C(N(O)CCC[C@@H](C(N[C@@H](CCCNO)C(O)=O)=O)N)=O)=O)=O)CCCN)=O)CO)=O)=CC=C1—
151752?—
1752-14
from: 1752-14
OC1=C(O)C(C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(N[C@@H](CO)C(N(O)CCC[C@@H](C(N[C@@H]2C(N(O)CCC2)=O)=O)N)=O)=O)=O)CCCN)=O)CO)=O)=CC=C1—
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