NPdia

BGC0001653PKS

Linfuranone B;Linfuranone C

Producing organism: Microbispora sp. GMKU363
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Streptosporangiales›Streptosporangiaceae›Microbispora
Biosynthetic class: PKS (Unknown)
Total steps: 10
DOI: 10.1021/acs.jnatprod.5c00434
MIBiG entry: View on MIBiG ↗

Biosynthetic (core)

Biosynthetic (additional)

Unknown

Domains

Ketosynthase (KS)

Acyltransferase (AT)

Dehydratase (DH)

Enoylreductase (ER)

Ketoreductase (KR)

Acyl carrier protein (ACP)

Acyl carrier (ACP)

Thioesterase (TE)

Docking N-term

Docking C-term

10 steps · 9 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`1653-1`	AP234_RS14725	M1	Methylmalonyl-CoA	`CCC(O)=O`	—
2	`1653-2`	AP234_RS14725	M2	1653-1;Malonyl-CoA from: 1653-1	`CCCCC(O)=O`	—
3	`1653-3`	AP234_RS37235;AP234_RS38650	M3	1653-2;Methylmalonyl-CoA from: 1653-2	`CCCCC([C@H](C)C(O)=O)=O`	{'Inactive': ['KR']}
4	`1653-4`	AP234_RS38650	M4	1653-3;Methylmalonyl-CoA from: 1653-3	`CCCCC([C@H](C)/C=C(C)/C(O)=O)=O`	—
5	`1653-5`	AP234_RS38650	M5	1653-4;Methylmalonyl-CoA from: 1653-4	`CCCCC([C@H](C)/C=C(C)/[C@H](O)[C@H](C)C(O)=O)=O`	—
6	`1653-6`	AP234_RS14715	M6	1653-5;Malonyl-CoA from: 1653-5	`CCCCC([C@H](C)/C=C(C)/[C@H](O)[C@H](C)/C=C/C(O)=O)=O`	—
7	`1653-7`	AP234_RS14715	M7	1653-6;Malonyl-CoA from: 1653-6	`CCCCC([C@H](C)/C=C(C)/[C@H](O)[C@H](C)/C=C/C=C/C(O)=O)=O`	—
8	`1653-8`	AP234_RS38645	M8	1653-7;Malonyl-CoA from: 1653-7	`CCCCC([C@H](C)/C=C(C)/[C@H](O)[C@H](C)/C=C/C=C/CCC(O)=O)=O`	—
9	`1653(1)`	AP234_RS14685	TE	1653-8 from: 1653-8	`CCCCC([C@H](C)/C=C(C)/[C@H](O)[C@H](C)/C=C/C=C/CCC(O)=O)=O`	—
10	`1653(2)`	?	—	1653(1)	`C[C@H](/C=C(C)/[C@H](O)[C@H](C)/C=C/C=C/CCC(O)=O)OC(CCCC)=O`	—

Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture