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BGC0001649PKS

Lavendiol

Producing organism
Streptomyces lavendulae
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
PKS (Unknown)
Total steps
9
DOI
MIBiG entry
View on MIBiG ↗

Gene Cluster Map31 genes · 55,095 bp

KSATKSATAmTKSKSATKSATKSAT10 kb55.1 kb visible · 55,095 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Other
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
KRKetoreductase (KR)
ACPAcyl carrier protein (ACP)
ACPAcyl carrier (ACP)
TEThioesterase (TE)
DnDocking N-term
DcDocking C-term
TDTerminal reductase
ACPSACP synthase
AmTAminotransferase III

Pathway Graphsteps arranged in biosynthetic order

9 steps · 8 edges
Step 1Load
lavA
+Malonyl-CoA
Step 2M1
lavA
+Malonyl-CoA
Step 3M2
lavA
+Malonyl-CoA
Step 4M3
lavA
+Malonyl-CoA
Step 5M4
lavB
+Malonyl-CoA
Inactive: KR
Step 6M5
lavB
+Malonyl-CoA
Step 7TE
lavB
Step 8
?
Step 9
BBA84055.1, ?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions9 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11649-1lavALoading
Malonyl-CoA
O=C(O)C—
21649-2lavAM1
1649-1;Malonyl-CoA
from: 1649-1
C/C=C/C(O)=O—
31649-3lavAM2
1649-2;Malonyl-CoA
from: 1649-2
C/C=C/C=C/C(O)=O—
41649-4lavAM3
1649-3;Malonyl-CoA
from: 1649-3
C/C=C/C=C/C=C/C(O)=O—
51649-5lavBM4
1649-4;Malonyl-CoA
from: 1649-4
C/C=C/C=C/C=C/C(CC(O)=O)=O{'Inactive': ['KR']}
61649-6lavBM5
1649-5;Malonyl-CoA
from: 1649-5
C/C=C/C=C/C=C/C(C[C@@H](O)CC(O)=O)=O—
71649-7lavBTE
1649-6
from: 1649-6
C/C=C/C=C/C=C/C(C[C@@H](O)CC=O)=O—
81649-8?—
1649-7
from: 1649-7
C/C=C/C=C/C=C/C(C[C@@H](O)CCO)=O—
91649BBA84055.1, ?—
1649-8
from: 1649-8
OCC[C@@H](C(C)C(/C=C/C=C/C=C/C)=O)O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture