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BGC0001628NRPS

JBIR-78;JBIR-95

Producing organism
Kibdelosporangium sp. AK-AA56
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Pseudonocardiales›Pseudonocardiaceae›Kibdelosporangium
Biosynthetic class
NRPS (Type I)
Total steps
14
DOI
—
MIBiG entry
View on MIBiG ↗
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C40H55N7O12825.39 Da

Gene Cluster Map9 genes · 35,856 bp

CACAECACAECACAECATE5 kb35.9 kb visible · 35,856 bp total
Biosynthetic (core)
Biosynthetic (additional)
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
CnCOM N-term
TEThioesterase (TE)
EEpimerization (E)
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

14 steps · 12 edges
Step 1
Start
Step 4
Start
Step 2
orf1, orf2
Step 5
orf3
Step 3M1
orf4
+L-Valine
Step 6M2
orf4
+(1628-5/L-Asparat…
Step 7M3
orf5
+L-Alanine
Step 8M4
orf5
+L-Leucine
Step 9M5
orf6
Step 10M6
orf6
+L-Alanine
Step 11M7
orf6
+L-Phenylalanine
Step 12TE
orf6
Step 13TE
orf6
Step 14TE
orf6
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions14 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11628-1Start—
O=C(C(O)=O)CC1=CC=CC=C1—
21628-2orf1, orf2—
1628-1
from: 1628-1
O=C(O)CC1=CC=CC=C1—
31628-3orf4M1
1628-2;L-Valine
from: 1628-2
O=C(N[C@H](C(O)=O)C(C)C)CC1=CC=CC=C1—
41628-4Start—
N[C@@H](C[R])C(O)=O—
51628-5orf3—
1628-4
from: 1628-4
N[C@@H](CS(=O)(O)=O)C(O)=O—
61628-6orf4M2
1628-3;(1628-5/L-Asparatic acid)
from: 1628-3
O=C(N[C@H](C(N[C@@H](C(O)=O)C[R])=O)C(C)C)CC1=CC=CC=C1—
71628-7orf5M3
1628-6;L-Alanine
from: 1628-6
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(O)=O)C)=O)C[R])=O)C(C)C)CC1=CC=CC=C1—
81628-8orf5M4
1628-7;L-Leucine
from: 1628-7
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(O)=O)=O)C)=O)C[R])=O)C(C)C)CC1=CC=CC=C1—
91628-9orf6M5
1628-8:Glycine
from: 1628-8:Glycine
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(O)=O)=O)=O)C)=O)C[R])=O)C(C)C)CC1=CC=CC=C1—
101628-10orf6M6
1628-9;L-Alanine
from: 1628-9
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(N[C@@H](C(O)=O)C)=O)=O)=O)C)=O)C[R])=O)C(C)C)CC1=CC=CC=C1—
111628-11orf6M7
1628-10;L-Phenylalanine
from: 1628-10
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(N[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)C)=O)=O)=O)C)=O)C[R])=O)C(C)C)CC2=CC=CC=C2—
121628-12orf6TE
1628-11
from: 1628-11
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(N[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)C)=O)=O)=O)C)=O)C[R])=O)C(C)C)CC2=CC=CC=C2—
131628(1)orf6TE
1628-11
from: 1628-11
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(N[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)C)=O)=O)=O)C)=O)CC(O)=O)=O)C(C)C)CC2=CC=CC=C2—
141628(2)orf6TE
1628-11
from: 1628-11
O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC(C)C)C(NCC(N[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)C)=O)=O)=O)C)=O)CS(=O)(O)=O)=O)C(C)C)CC2=CC=CC=C2—
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