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BGC0001570NRPS

Deimino-antipain

Producing organism
Streptomyces noursei
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I)
Total steps
6
DOI
MIBiG entry
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deimino-antipain
C27H43N9O7605.70 Da

Gene Cluster Map9 genes · 15,484 bp

CAAACKR2 kb15.5 kb visible · 15,484 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Unknown
Domains
KRKetoreductase (KR)
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1
A4V12_31650
+Phenylalanine
Step 2
?
+Acetyl-CoA
Step 3
A4V12_31645, ?
+Arginine
Step 4
A4V12_31635;A4V12_31655
+Valine
Step 5
A4V12_31645
+Arginine
Step 6MR
A4V12_31645
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11570-1A4V12_31650—
Phenylalanine
O=C([C@@H](N)CC1=CC=CC=C1)O—
21570-2?—
1570-1;Acetyl-CoA
from: 1570-1
O=C([C@@H](NC(O)=O)CC1=CC=CC=C1)O—
31570-3A4V12_31645, ?—
1570-2;Arginine
from: 1570-2
O=C([C@@H](NC(N[C@H](C(O)=O)CCCNC(N)=O)=O)CC1=CC=CC=C1)O—
41570-4A4V12_31635;A4V12_31655—
1570-3;Valine
from: 1570-3
O=C([C@@H](NC(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CCCNC(N)=O)=O)CC1=CC=CC=C1)O—
51570-5A4V12_31645—
1570-4;Arginine
from: 1570-4
O=C([C@@H](NC(N[C@H](C(N[C@H](C(NC(C(O)=O)CCCNC(N)=N)=O)C(C)C)=O)CCCNC(N)=O)=O)CC1=CC=CC=C1)O—
61570A4V12_31645MR
1570-5
from: 1570-5
O=C([C@@H](NC(N[C@H](C(N[C@H](C(NC(C([H])=O)CCCNC(N)=N)=O)C(C)C)=O)CCCNC(N)=O)=O)CC1=CC=CC=C1)O—
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