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BGC0001569NRPS

Dechlorocuracomycin

Producing organism
Streptomyces noursei ATCC 11455
Taxonomy
BacteriaActinomycetotaActinomycetesKitasatosporalesStreptomycetaceaeStreptomyces
Biosynthetic class
NRPS (Type I)
Total steps
7
DOI
MIBiG entry
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dechlorocuracomycin
C37H57N9O8755.43 Da

Gene Cluster Map24 genes · 46,257 bp

AmTTauDCACAEACAECAECA10 kb46.3 kb visible · 46,257 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Other
Unknown
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
TEThioesterase (TE)
EEpimerization (E)
AmTAminotransferase IV
TauDTauD oxygenase
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

7 steps · 6 edges
Step 1M1
SNOUR_12645
+Tryptophan
Step 2M2
SNOUR_12645
+Valine
Step 3M3
SNOUR_12645
+Leucine
Step 4M4
SNOUR_12645
+Isoleucine
Step 5M5
SNOUR_12640
+Ornithine
Step 6M6
SNOUR_12640
+Asparagine
Step 7
?
Starting stepIntermediateFinal productModuleLoadingTENo modulePKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions7 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11569-1SNOUR_12645M1
Tryptophan
N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2
21569-2SNOUR_12645M2
1569-1;Valine
from: 1569-1
N[C@H](C(N[C@@H](C(O)=O)C(C)C)=O)CC1=CNC2=C1C=CC=C2
31569-3SNOUR_12645M3
1569-2;Leucine
from: 1569-2
N[C@H](C(N[C@@H](C(C[C@@H](C(O)=O)CC(C)C)=O)C(C)C)=O)CC1=CNC2=C1C=CC=C2
41569-4SNOUR_12645M4
1569-3;Isoleucine
from: 1569-3
N[C@H](C(N[C@@H](C(C[C@@H](C(N[C@H](C(O)=O)[C@@H](C)CC)=O)CC(C)C)=O)C(C)C)=O)CC1=CNC2=C1C=CC=C2
51569-5SNOUR_12640M5
1569-4;Ornithine
from: 1569-4
N[C@H](C(N[C@@H](C(C[C@@H](C(N[C@H](C(C[C@H](C(O)=O)CCCN)=O)[C@@H](C)CC)=O)CC(C)C)=O)C(C)C)=O)CC1=CNC2=C1C=CC=C2
61569-6SNOUR_12640M6
1569-5;Asparagine
from: 1569-5
N[C@H](C(N[C@@H](C(C[C@@H](C(N[C@H](C(C[C@H](C(NC(C(O)=O)C(C(N)=O)O)=O)CCCN)=O)[C@@H](C)CC)=O)CC(C)C)=O)C(C)C)=O)CC1=CNC2=C1C=CC=C2
71569?
1569-6
from: 1569-6
O=C(C(C(C(N)=O)O)NC([C@H](CCCN)NC([C@H](C(CC)C)NC1=O)=O)=O)N[C@@H](CC2=CNC3=C2C=CC=C3)C(N[C@H](C(C)C)C(N[C@@H]1CC(C)C)=O)=O
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture