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BGC0001504PKS

Amycomicin

Producing organism
Amycolatopsis sp. AA4
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Pseudonocardiales›Pseudonocardiaceae›Amycolatopsis
Biosynthetic class
PKS (Unknown)
Total steps
7
DOI
—
MIBiG entry
View on MIBiG ↗

Gene Cluster Map8 genes · 13,734 bp

AKSKSATDHERKRACPTauD2 kb13.7 kb visible · 13,734 bp total
Biosynthetic (core)
Biosynthetic (additional)
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
EREnoylreductase (ER)
KRKetoreductase (KR)
ACPAcyl carrier (ACP)
AAdenylation (A)
ACPAcyl carrier (ACP)
TauDTauD oxygenase

Pathway Graphsteps arranged in biosynthetic order

7 steps · 6 edges
Step 1
Start
Step 2
CU254_21775
+Glycine
Step 3
CU254_21790
Step 4
CU254_21770, CU254_21755
Step 5
CU254_21765, CU254_21760
Iterative
Step 6
?
Step 7
CU254_21780, CU254_2178…
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions7 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11504-1Start—
O=C(/C=C/C=C/C)[R]—
21504-2CU254_21775—
1504-1;Glycine
from: 1504-1
O=C(CC(NCC(O)=O)/C=C/C)O—
31504-3CU254_21790—
1504-2
from: 1504-2
O=C(C[C@H]([N+]#[C-])/C=C/C)O—
41504-4CU254_21770, CU254_21755—
1504-3
from: 1504-3
O=C(C[C@H]([N+]#[C-])/C=C/C)O—
51504-5CU254_21765, CU254_21760—
1504-4
from: 1504-4
O[C@H](C[C@H]([N+]#[C-])/C=C/C)CCCCCCCCCCCC(O)=O{'Iteration': [(['DH'], 'Mal…
61504-6?—
1504-5
from: 1504-5
O[C@H](C[C@H]([N+]#[C-])/C=C/C)CCCCCCCCCCCC(O)=O—
71504CU254_21780, CU254_21785, ?—
1504-6
from: 1504-6
O[C@H]([C@H](O1)[C@]1([N+]#[C-])/C=C/C)CCCCC(CCCCCCC(O)=O)=O—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture