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BGC0001386PKS

JBIR-76;JBIR-77

Producing organism
Streptomyces sp. RI-77
Taxonomy
BacteriaActinomycetotaActinomycetesKitasatosporalesStreptomycetaceaeStreptomyces
Biosynthetic class
PKS (Unknown)
Total steps
10
DOI
MIBiG entry
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C15H14O7306.07 Da

Gene Cluster Map25 genes · 25,601 bp

KRCycKSKSER5 kb25.6 kb visible · 25,601 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Other
Unknown
Domains
KSKetosynthase (KS)
EREnoylreductase (ER)
KRKetoreductase (KR)
ACPAcyl carrier (ACP)
CycPolyketide cyclase
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

10 steps · 9 edges
Step 1
?
+Acetyl-CoA, Malonyl-CoA
Step 2
ifnJ, ifnK
Step 3
?
Step 4
?
Step 5
ifnQ
Step 6
ifnF?
Step 7
?
Step 8
?
Step 9
(ifnH, ifnR, infS)?
Step 10
(ifnH, ifnR, infS)?
Starting stepIntermediateFinal productModuleLoadingTENo modulePKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions10 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11386-1?
Acetyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA
O=C(C)CC(CC(CC(CC(CC(CC(CC(O)=O)=O)=O)=O)=O)=O)=O
21386-2ifnJ, ifnK
1386-1
from: 1386-1
O=C(C)C1=C(O)C2=C(C=C1CC(CC(O)=O)=O)C=C(O)C=C2O
31386-3?
1386-2
from: 1386-2
O=C(C)C1=C(O)C2=C(C=C1CC(CC(O)=O)=O)C=C(O)C=C2O
41386-4?
1386-3
from: 1386-3
O=C(C)C1=C(O)C2=C(C=C1CC(C)=O)C=C(O)C=C2O
51386-5ifnQ
1386-4
from: 1386-4
O=C(C)C1=C(O)C2=C(C=C1COC(C[R])=O)C=C(O)C=C2O
61386-6ifnF?
1386-5
from: 1386-5
OCC(CC1=C(C2=O)C(O)=CC(O)=C1)=C2C(C)=O
71386-7?
1386-6
from: 1386-6
O=C1C2=C(CC3=C1C(O)(C)OC3)C=C(O)C=C2O
81386-8?
1386-7
from: 1386-7
O=C1C2=C(CC3C1=C(C)OC3)C=C(O)C=C2O
91386(1)(ifnH, ifnR, infS)?
1386-8
from: 1386-8
O=C1C2=C(C(OC)C3C1=C(CO)OC3)C=C(O)C(OC)=C2O
101386(2)(ifnH, ifnR, infS)?
1386-8
from: 1386-8
O=C1C2=C(C(OC)C3C1=C(C[H])OC3)C=C(O)C(OC)=C2O
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