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BGC0001366PKS

BE-24566B;Zunyimycin A

Producing organism
Streptomyces sp. FJS31-2
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
PKS (Unknown)
Total steps
6
DOI
MIBiG entry
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C27H24O7460.15 Da

Gene Cluster Map16 genes · 15,462 bp

KSKSCyc2 kb15.5 kb visible · 15,462 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Unknown
Domains
KSKetosynthase (KS)
ACPAcyl carrier protein (ACP)
CycPolyketide cyclase

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1
ctg1_orf7, ctg1_orf8, c…
+Malonyl-CoA, Malonyl-CoA
Step 2
ctg1_orf11, ?
Step 3
ctg1_orf10, ?
Step 4
ctg1_orf14, ?
Step 5
ctg1_orf12, ctg1_orf5
Step 6
ctg1_orf12, ctg1_orf5
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11366-1ctg1_orf7, ctg1_orf8, ctg1_orf9—
Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA;Malonyl-CoA
O=C(CC(CC(CC(CC(CC(CC(CC(CC(O)=O)=O)=O)=O)=O)=O)=O)=O)CC(CC(CC(CC(C)=O)=O)=O)=O—
21366-2ctg1_orf11, ?—
1366-1
from: 1366-1
OC1=CC2=C(C(C3=C(O)C(C(O)C4=C(C)C=C(O)C=C4O)=C(CC(C)=O)C=C3C2)=O)C(O)=C1—
31366-3ctg1_orf10, ?—
1366-2
from: 1366-2
OC1=CC2=C(C(C3=C(O)C(C(O4)C5=C(C)C=C(O)C=C5OC4(C)C6)=C6C=C3C2)=O)C(O)=C1—
41366-4ctg1_orf14, ?—
1366-3
from: 1366-3
OC1=CC2=C(C(C3=C(O)C(C(O4)C5=C(C)C=C(O)C=C5OC4(C)C6)=C6C=C3C2(C)C)=O)C(O)=C1—
51366(1)ctg1_orf12, ctg1_orf5—
1366-4
from: 1366-4
OC1=C([H])C2=C(C(C3=C(O)C(C(O4)C5=C(C)C([H])=C(O)C([H])=C5OC4(C)C6)=C6C=C3C2(C)C)=O)C(O)=C1[H]—
61366(2)ctg1_orf12, ctg1_orf5—
1366-4
from: 1366-4
OC1=C(Cl)C2=C(C(C3=C(O)C(C(O4)C5=C(C)C([H])=C(O)C(Cl)=C5OC4(C)C6)=C6C=C3C2(C)C)=O)C(O)=C1[H]—
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