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BGC0001341NRPS

Valinomycin

Producing organism
Rothia nasimurium
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Micrococcales›Micrococcaceae›Rothia
Biosynthetic class
NRPS (Type I)
Total steps
6
DOI
MIBiG entry
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valinomycin
C54H90N6O181110.63 Da

Gene Cluster Map5 genes · 20,822 bp

AKRCATEAKRCAEC5 kb20.8 kb visible · 20,822 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Unknown
Domains
KRKetoreductase (KR)
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
ACPAcyl carrier (ACP)
TEThioesterase (TE)
EEpimerization (E)
ACPSACP synthase

Pathway Graphsteps arranged in biosynthetic order

6 steps · 5 edges
Step 1M1
A7979_04525
+α-Ketoisovalerate
Step 2M2
A7979_04525
+L-Valine
Step 3M3
A7979_04520
+Pyruvate
Step 4M4
A7979_04520
+L-Valine
Step 5TE
A7979_04520
Step 6
?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions6 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
11341-1A7979_04525M1
α-Ketoisovalerate
O[C@@H](C(O)=O)C(C)C—
21341-2A7979_04525M2
1341-1;L-Valine
from: 1341-1
O[C@@H](C(N[C@@H](C(O)=O)C(C)C)=O)C(C)C—
31341-3A7979_04520M3
1341-2;Pyruvate
from: 1341-2
O[C@@H](C(N[C@@H](C(O[C@H](C(O)=O)C)=O)C(C)C)=O)C(C)C—
41341-4A7979_04520M4
1341-3;L-Valine
from: 1341-3
O[C@@H](C(N[C@@H](C(O[C@H](C(N[C@H](C(O)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C—
51341-5A7979_04520TE
1341-4
from: 1341-4
O[C@@H](C(N[C@@H](C(O[C@H](C(N[C@H](C(O)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C—
61341?—
1341-5;1341-5;1341-5
from: 1341-5, 1341-5, 1341-5
O=C1[C@H](NC([C@H](OC([C@@H](NC([C@@H](OC([C@H](NC([C@H](OC([C@@H](NC([C@@H](OC([C@H](NC([C@H](OC([C@@H](NC([C@@H](O1)C(C)C)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)C)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)C)=O)C(C)C—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture