NPdia

BGC0001328Hybrid

Rakicidin A;Rakicidin B

Producing organism: Micromonospora sp. M42
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Micromonosporales›Micromonosporaceae›Micromonospora
Biosynthetic class: NRPS (Type I);PKS (Type I)
Total steps: 11
DOI: 10.1186/s40793-016-0206-2
MIBiG entry: —

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C₃₂H₅₄N₄O₇606.40 Da

11 steps · 10 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions11 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`1328-1`	MCBG_00130	—	?	`O=C([R])O`	—
2	`1328-2`	MCBG_00130;MCBG_00131;MCBG_00132	—	1328-1;Methylmalonyl-CoA from: 1328-1	`[R]CC(C(O)=O)C`	—
3	`1328-3`	MCBG_00133;MCBG_00134	—	1328-2;Methylmalonyl-CoA from: 1328-2	`[R]CC(C(O)C(C(O)=O)C)C`	—
4	`1328-4`	MCBG_00135	—	1328-3;Serine from: 1328-3	`[R]CC(C(O)C(C(NC(C(O)=O)CO)=O)C)C`	—
5	`1328-5`	MCBG_00136;MCBG_00137	—	1328-4;Malonyl-CoA from: 1328-4	`[R]CC(C(O)C(C(NC(/C=C/C(O)=O)=C)=O)C)C`	—
6	`1328-6`	MCBG_00138;MCBG_00139	—	1328-5;Glycine from: 1328-5	`[R]CC(C(O)C(C(NC(/C=C/C(N(CC(O)=O)C)=O)=C)=O)C)C`	—
7	`1328-7`	MCBG_00139;MCBG_00140	—	1328-6;Asparagine from: 1328-6	`[R]CC(C(O)C(C(NC(/C=C/C(N(CC(NC(C(O)=O)CC(N)=O)=O)C)=O)=C)=O)C)C`	—
8	`1328-8`	?	—	1328-7 from: 1328-7	`C=C(/C=C/C(N(CC(NC1C(N)=O)=O)C)=O)NC(C(C)C(C(C[R])C)OC1=O)=O`	—
9	`1328-9`	MCBG_00144	—	1328-8 from: 1328-8	`C=C(/C=C/C(N(CC(NC1C(O)C(N)=O)=O)C)=O)NC(C(C)C(C(C[R])C)OC1=O)=O`	—
10	`1328(1)`	MCBG_00144	—	1328-8 from: 1328-8	`C=C(/C=C/C(N(CC(NC1C(C(N)=O)O)=O)C)=O)NC(C(C)C(C(CCCCCCCCCCCC(C)C)C)OC1=O)=O`	—
11	`1328(2)`	MCBG_00144	—	1328-8 from: 1328-8	`C=C(/C=C/C(N(CC(NC1C(C(N)=O)O)=O)C)=O)NC(C(C)C(C(CCCCCCCCCCCCC(C)C)C)OC1=O)=O`	—

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