NPdia

BGC0001296PKS

Streptazone E

Producing organism: Streptomyces sp. MSC090213JE08
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: PKS (Unknown)
Total steps: 13
DOI: 10.1002/cbic.201500317
MIBiG entry: View on MIBiG ↗

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streptazone E

C₁₂H₁₃NO187.10 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Unknown

Domains

Ketosynthase (KS)

Acyltransferase (AT)

Dehydratase (DH)

Ketoreductase (KR)

Acyl carrier protein (ACP)

Acyl carrier (ACP)

Thioesterase (TE)

Docking N-term

Docking C-term

Terminal reductase

Aminotransferase III

13 steps · 12 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`1296-1`	stzD	Loading	Malonyl-CoA	`O=C(C)O`	—
2	`1296-2`	stzD	M1	1296-1;Malonyl-CoA from: 1296-1	`C/C=C/C(O)=O`	—
3	`1296-3`	stzD	M2	1296-2;Malonyl-CoA from: 1296-2	`C/C=C/C=C/C(O)=O`	—
4	`1296-4`	stzC	M3	1296-3;Malonyl-CoA from: 1296-3	`C/C=C/C=C/C=C/C(O)=O`	—
5	`1296-5`	stzC	M4	1296-4;Malonyl-CoA from: 1296-4	`C/C=C/C=C/C=C/C(CC(O)=O)=O`	{'Inactive': ['KR']}
6	`1296-6`	stzB	M5	1296-5;Malonyl-CoA from: 1296-5	`C/C=C/C=C/C=C/C(C/C=C/C(O)=O)=O`	—
7	`1296-7`	stzB	MR	1296-6 from: 1296-6	`C/C=C/C=C/C=C/C(C/C=C/C=O)=O`	—
8	`1296-8`	?	—	1296-7 from: 1296-7	`C/C=C/C=C/C=C/C(CCCC=O)=O`	—
9	`1296-9`	stzH	—	1296-8 from: 1296-8	`C/C=C/C=C/C=C/C(CCCCN)=O`	—
10	`1296-10`		—	1296-9 from: 1296-9	`C/C=C/C=C/C=C/C1=NCCCC1`	—
11	`1296-11`	stzI, stzJ	—	1296-10 from: 1296-10	`C/C=C/C=C/C=C/C1=NCCC=C1`	—
12	`1296-12`	stzK, stzG	—	1296-11 from: 1296-11	`C/C=C/C=C/C=C/C1=NCCC2C1O2`	—
13	`1296`	stzE, stzF	—	1296-12 from: 1296-12	`O=C1CCNC2=C1/C(C=C2)=C/C=C/C`	—

Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture