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BGC0000996Hybrid

Frontalamide B

Producing organism
Streptomyces sp. SPB78
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I);PKS (Iterative type I)
Total steps
7
DOI
MIBiG entry
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C29H36N2O6508.26 Da

Gene Cluster Map7 genes · 16,575 bp

KSATDHKRACPCAER2 kb16.6 kb visible · 16,575 bp total
Biosynthetic (core)
Biosynthetic (additional)
Unknown
Domains
KSKetosynthase (KS)
ATAcyltransferase (AT)
DHDehydratase (DH)
EREnoylreductase (ER)
KRKetoreductase (KR)
ACPAcyl carrier (ACP)
CCondensation (C)
AAdenylation (A)

Pathway Graphsteps arranged in biosynthetic order

7 steps · 6 edges
Step 1
SSLG_04251
{'iteration': [((None), ‘M…
Step 3
SSLG_04251
{'iteration': [((None), ‘M…
Step 2
SSLG_04251
+Ornithine
Step 4
SSLG_04251
Step 5TE
SSLG_04251
Step 6
?
Step 7
?
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions7 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
1996-1SSLG_04251—
O=C(C)CC(CC(C/C=C/C(CC(O)=O)=O)=O)=O{'iteration': [((None), ‘Mal…
2996-2SSLG_04251—
996-1;Ornithine
from: 996-1
O=C(C)CC(CC(C/C=C/C(CC(NC(C(O)=O)CCCN)=O)=O)=O)=O—
3996-3SSLG_04251—
OC(/C=C/CC(CC(CC(CC(C)=O)=O)=O)=O)=O{'iteration': [((None), ‘Mal…
4996-4SSLG_04251—
996-2;996-3
from: 996-2, 996-3
O=C(/C=C/CC(CC(CC(CC(C)=O)=O)=O)=O)NCCCC(C(O)=O)NC(CC(/C=C/CC(CC(CC(C)=O)=O)=O)=O)=O—
5996-5SSLG_04251TE
996-4
from: 996-4
O=C(CC(CC(CC(C)=O)=O)=O)C/C=C/C(NCCCC1C(O)=C(C(/C=C/CC(CC(CC(C)=O)=O)=O)=O)C(N1)=O)=O—
6996-6?—
996-5
from: 996-5
CC1C(C(C(CC(/C=C/C2=O)C3C/C=C\C(NCCCC4C(O)=C2C(N4)=O)=O)=O)C3C5)C5CC1C=C—
7996?—
996-6
from: 996-6
CC1C(C(C(CC(/C=C/C2=O)C3C/C=C\C(NCCC(O)C4C(O)=C2C(N4)=O)=O)=O)C3C5)C5CC1C=C—
Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture