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BGC0000423NRPS

scabiechelin

Producing organism
Streptomyces scabiei 87.22
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class
NRPS (Type I)
Total steps
9
DOI
MIBiG entry
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scabichelin
C26H49N9O10647.36 Da

Gene Cluster Map10 genes · 30,020 bp

AMTCACAMTCACAE5 kb30.0 kb visible · 30,020 bp total
Biosynthetic (core)
Biosynthetic (additional)
Transport
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
EEpimerization (E)
MTMethyltransferase
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

9 steps · 11 edges
Step 1
start
+L-Ornithine
Step 2
SCAB_85521
Step 3
SCAB_85511
Step 4M1
SCAB_85471
Step 5M2
SCAB_85471
+Serine
Step 6M3
SCAB_85471
Step 7M4
SCAB_85471
Step 8M5
SCAB_85471
Step 9
SCAB_85471
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions9 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
1423-1start—
L-Ornithine
O=C(O)[C@@H](N)CCCN—
2423-2SCAB_85521—
423-1
from: 423-1
O=C(O)[C@@H](N)CCCNO—
3423-3SCAB_85511—
423-2
from: 423-2
O=C(O)[C@@H](N)CCCN(C([H])=O)O—
4423-4SCAB_85471M1
423-3
from: 423-3
ON(C([H])=O)CCC[C@H](NC)C(O)=O—
5423-5SCAB_85471M2
423-4;Serine
from: 423-4
ON(C([H])=O)CCC[C@H](NC)C(N[C@H](C(O)=O)CO)=O—
6423-6SCAB_85471M3
423-5;423-2
from: 423-5, 423-2
ON(C([H])=O)CCC[C@H](NC)C(N[C@H](C(N(O)CCC[C@H](NC)C(O)=O)=O)CO)=O—
7423-7SCAB_85471M4
423-6;423-1
from: 423-6, 423-1
ON(C([H])=O)CCC[C@H](NC)C(N[C@H](C(N(O)CCC[C@H](NC)C(N[C@H](C(O)=O)CCCN)=O)=O)CO)=O—
8423-8SCAB_85471M5
423-7;423-2
from: 423-7, 423-2
ON(C([H])=O)CCC[C@H](NC)C(N[C@H](C(N(O)CCC[C@H](NC)C(N[C@H](C(N[C@@H](C(O)=O)CCCCNO)=O)CCCN)=O)=O)CO)=O—
9423SCAB_85471—
423-8
from: 423-8
ON(C([H])=O)CCC[C@H](NC)C(N[C@H](C(N(O)CCC[C@H](NC)C(N[C@H](C(N[C@@H]1CCCN(O)C1=O)=O)CCCN)=O)=O)CO)=O—
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