NPdia

BGC0000392NRPS

mirubactin

Producing organism: Actinosynnema mirum DSM 43827
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Pseudonocardiales›Pseudonocardiaceae›Actinosynnema
Biosynthetic class: NRPS (Type I)
Total steps: 9
DOI: 10.1021/np300046k
MIBiG entry: View on MIBiG ↗

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Other

Unknown

Domains

Ketoreductase (KR)

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Epimerization (E)

TIGR01720

9 steps · 9 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`392-1`	?	Loading	2,3-dihydroxybenzoate	`OC1=C(O)C=CC=C1C(O)=O`	—
2	`392-2`	Amir_2726;?	Loading	392-1 from: 392-1	`OC1=C(O)C=CC=C1C(O)=O`	—
3	`392-3`	Amir_2719	M1	392-2;Arginine from: 392-2	`OC1=C(O)C=CC=C1C(N[C@H](CCCNC(N)=N)C(O)=O)=O`	—
4	`392-4`	start	—	Ornithine	`OC(C(N)CCCN)=O`	—
5	`392-5`	?	—	392-4 from: 392-4	`OC(C(N)CCCNO)=O`	—
6	`392-6`	?	—	392-5 from: 392-5	`OC(C(N)CCCN(C([H])=O)O)=O`	—
7	`392-7`	Amir_2719	M2	392-3;392-6 from: 392-3, 392-6	`OC1=C(O)C=CC=C1C(N[C@H](CCCNC(N)=N)C(NC(CCCN(O)C([H])=O)C(O)=O)=O)=O`	—
8	`392-8`	Amir_2719	M3	392-7;392-2 from: 392-7, 392-2	`OC1=C(O)C=CC=C1C(N[C@H](CCCNC(N)=N)C(NC(CCCN(OC(C2=C(O)C(O)=CC=C2)=O)C([H])=O)C(O)=O)=O)=O`	—
9	`392`	?	—	392-8 from: 392-8	`OC1=C(O)C=CC=C1C(N[C@H](CCCNC(N)=N)C(NC(CCCN(OC(C2=C(O)C(O)=CC=C2)=O)C([H])=O)C(O)=O)=O)=O`	—

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