NPdia

BGC0000388NRPS

mannopeptimycin

Producing organism: Streptomyces hygroscopicus
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces›Streptomyces violaceusniger group
Biosynthetic class: NRPS (Type I)
Total steps: 7
DOI: 10.1128/AAC.01545-05
MIBiG entry: View on MIBiG ↗

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mannopeptimycin

C₅₈H₈₆N₁₂O₂₆+₂1366.58 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Unknown

Domains

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Epimerization (E)

Aminotransferase I/II

TauD oxygenase

TIGR01720

7 steps · 6 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`388-1`	mppA	Loading	Serine	`O=C([C@H](CO)N)O`	—
2	`388-2`	mppA	M1	388-1;Glycine from: 388-1	`OC(CNC([C@H](CO)N)=O)=O`	—
3	`388-3`	mppA	M2	388-2;Phenylalanine from: 388-2	`O=C(N[C@@H](CC1=CC=CC=C1)C(O)=O)CNC([C@H](CO)N)=O`	—
4	`388-4`	mppB	M3	388-3;Tyrosine from: 388-3	`O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(O)=O)CC2=CC=C(O)C=C2)=O)CNC([C@H](CO)N)=O`	—
5	`388-5`	mppB	M4	388-4;beta-hydroxy-enduracididine from: 388-4	`O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(N[C@@H]([C@H](C(N2)CNC2=N)O)C(O)=O)=O)CC3=CC=C(O)C=C3)=O)CNC([C@H](CO)N)=O`	—
6	`388-6`	mppB	M5	388-5;beta-hydroxy-enduracididine from: 388-5	`O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(N[C@@H]([C@H](C(N2)CNC2=N)O)C(N[C@H]([C@@H](C(N3)CNC3=N)O)C(O)=O)=O)=O)CC4=CC=C(O)C=C4)=O)CNC([C@H](CO)N)=O`	{'Domain_Reuse': ['A', (mpp,…
7	`388`	mppK?	—	388-6 from: 388-6	`O=C(N[C@@H](CO)C(NCC1=O)=O)[C@H](NC([C@H]([C@H](O)C2NC(NC2)=N)NC([C@@H](CC3=CC=C(O)C=C3)NC([C@H](CC4=CC=CC=C4)N1)=O)=O)=O)[C@@H](O)C(N5)CNC5=N`	—

Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture