NPdia

BGC0000366NRPS

gobichelin A;gobichelin B

Producing organism: Streptomyces sp. NRRL F-4415
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: NRPS (Type I)
Total steps: 9
DOI: 10.1039/c2md20232h
MIBiG entry: View on MIBiG ↗

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C₃₀H₄₁N₉O₉671.30 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Unknown

Domains

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Acyl carrier (ACP)

COM N-term

COM C-term

Thioesterase (TE)

Epimerization (E)

Heterocyclization (Cy)

TIGR01720

9 steps · 8 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`366-1`	start	—	Chorismic acid	`O[C@@H]1C=CC(C(O)=O)=C[C@H]1OC(C(O)=O)=C`	—
2	`366-2`	gobH	Loading	366-1 from: 366-1	`O=C(O)C1=C(O)C=CC=C1`	—
3	`366-3`	gobJ	M1	366-2;Serine from: 366-2	`OC([C@H]1N=C(OC1)C2=C(O)C=CC=C2)=O`	—
4	`366-4`	gobR	M2	366-3;Histidine from: 366-3	`O=C(O)[C@H](CC1=CN=CN1)NC([C@H]2N=C(OC2)C3=C(O)C=CC=C3)=O`	—
5	`366-5`	gobR	M3	366-4;Lysine from: 366-4	`O=C(NC(C(O)=O)CCCCN)[C@H](CC1=CN=CN1)NC([C@H]2N=C(OC2)C3=C(O)C=CC=C3)=O`	—
6	`366-6`	gobS	M4	366-5;Serine from: 366-5	`O=C(NC(C(N[C@@H](CO)C(O)=O)=O)CCCCN)[C@H](CC1=CN=CN1)NC([C@H]2N=C(OC2)C3=C(O)C=CC=C3)=O`	—
7	`366-7`	gobS	M5	366-6;N-hydroxyl-ornithine from: 366-6	`O=C(NC(C(N[C@@H](CO)C(N[C@@H](C(O)=O)CCCNO)=O)=O)CCCCN)[C@H](CC1=CN=CN1)NC([C@H]2N=C(OC2)C3=C(O)C=CC=C3)=O`	—
8	`366(1)`	gobS	TE	366-7 from: 366-7	`O=C(NC(C(N[C@@H](CO)C(N[C@H]1CCCN(O)C1=O)=O)=O)CCCCN)[C@H](CC2=CN=CN2)NC([C@H]3N=C(OC3)C4=C(O)C=CC=C4)=O`	—
9	`366(2)`	gobS	TE	366-7 from: 366-7	`O=C(NC(C(N[C@@H](CO)C(N[C@H]1CCCN(O)C1=O)=O)=O)CCCCN)[C@H](CC2=CN=CN2)NC([C@H](CO)NC(C3=C(O)C=CC=C3)=O)=O`	—

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