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BGC0000349NRPS

erythrochelin

Producing organism
Saccharopolyspora erythraea NRRL 2338
Taxonomy
Bacteria›Actinomycetota›Actinomycetes›Pseudonocardiales›Pseudonocardiaceae›Saccharopolyspora
Biosynthetic class
NRPS (Type I)
Total steps
8
DOI
MIBiG entry
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erythrochelin
C24H41N7O11603.29 Da

Gene Cluster Map7 genes · 24,145 bp

CAETgrCAETgrCACAC5 kb24.1 kb visible · 24,145 bp total
Biosynthetic (core)
Biosynthetic (additional)
Regulatory
Transport
Domains
CCondensation (C)
AAdenylation (A)
PCPPeptidyl carrier (PCP)
EEpimerization (E)
TgrTIGR01720

Pathway Graphsteps arranged in biosynthetic order

8 steps · 9 edges
Step 1
start
+L-Ornithine
Step 2
SACE_3033
Step 3
?
+Malonyl-CoA
Step 4M1
SACE_3035
+Acetyl-CoA
Step 5M2
SACE_3035
+Serine
Step 6M3
SACE_3035
Step 7M4
SACE_3035
Step 8
SACE_3035
Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions8 steps

StepProduct IDEnzymeModuleSubstrateProduct SMILESNotes
1349-1start—
L-Ornithine
NCCC[C@H](N)C(O)=O—
2349-2SACE_3033—
349-1
from: 349-1
ONCCC[C@H](N)C(O)=O—
3349-3?—
349-2;Malonyl-CoA
from: 349-2
OC([C@@H](CCCN(O)C(C)=O)NC(C)=O)=O—
4349-4SACE_3035M1
349-3;Acetyl-CoA
from: 349-3
O=C(N[C@@H](C(O)=O)CCCN(C(C)=O)O)C—
5349-5SACE_3035M2
349-4;Serine
from: 349-4
OC([C@@H](CO)NC([C@@H](CCCN(O)C(C)=O)NC(C)=O)=O)=O—
6349-6SACE_3035M3
349-5;349-2
from: 349-5, 349-2
OC([C@@H](N)CCCN(O)C([C@H](CO)NC(C(CCCN(O)C(C)=O)NC(C)=O)=O)=O)=O—
7349-7SACE_3035M4
349-6;349-3
from: 349-6, 349-3
O=C([C@H](CCCN(O)C(C)=O)NC([C@@H](N)CCCN(O)C([C@H](CO)NC(C(CCCN(O)C(C)=O)NC(C)=O)=O)=O)=O)O—
8349SACE_3035—
349-7
from: 349-7
ON(CCC[C@@H]1NC([C@H](CCCN(O)C(C)=O)NC1=O)=O)C(C(CO)NC([C@@H](CCCN(O)C(C)=O)NC(C)=O)=O)=O—
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