NPdia

BGC0000325NRPS

coelichelin

Producing organism: Streptomyces coelicolor A3(2)
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces›Streptomyces albidoflavus group
Biosynthetic class: NRPS (Type I)
Total steps: 5
DOI: 10.1038/nchembio731
MIBiG entry: View on MIBiG ↗

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coelichelin

C₂₁H₃₉N₇O₁₁565.27 Da

Biosynthetic (core)

Biosynthetic (additional)

Transport

Domains

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Epimerization (E)

TIGR01720

5 steps · 5 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`325-1`	SCO0492	M1	L-δ-N-formyl-δ-N-hydroxyornithine	`[H]C(N(CCC[C@@H](N)C(O)=O)O)=O`	—
2	`325-2`	SCO0492	M2	325-1;L-threonine from: 325-1	`[H]C(N(CCC[C@@H](N)C(N[C@@]([C@@H](C)O)([H])C(O)=O)=O)O)=O`	—
3	`325-3`	SCO0492	M3	325-2;L-δ-N-hydroxyornithin from: 325-2	`[H]C(N(CCC[C@@H](N)C(N[C@@]([C@@H](C)O)([H])C(N(O)CCC[C@H](N)C(O)=O)=O)=O)O)=O`	—
4	`325-4`	SCO0492	—	325-1;325-3 from: 325-1, 325-3	`[H]C(N(CCC[C@@H](N)C(N[C@@]([C@@H](C)O)([H])C(N(O)CCC[C@H](NC([C@H](N)CCCN(O)C([H])=O)=O)C(O)=O)=O)=O)O)=O`	—
5	`325`	SCO0490	—	325-4 from: 325-4	`O=C([H])N(O)CCC[C@@H](N)C(N[C@@]([C@H](O)C)([H])C(N(O)CCC[C@@H](C(O)=O)NC([C@H](N)CCCN(C([H])=O)O)=O)=O)=O`	—

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