NPdia

BGC0000319NRPS

cephamycin C

Producing organism: Streptomyces clavuligerus
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: NRPS (Type I)
Total steps: 9
DOI: 10.1023/A:1001804925843
MIBiG entry: View on MIBiG ↗

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cephamycin C

C₁₆H₂₂N₄O₉S446.11 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Resistance

Unknown

Domains

Condensation (C)

Adenylation (A)

Peptidyl carrier (PCP)

Thioesterase (TE)

Epimerization (E)

Aminotransferase III

Aminotransferase V

9 steps · 8 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions9 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`319-1`	SSCG_00146	M1	L-α-Aminoadipic acid	`NC(C(O)=O)CCCC(O)=O`	—
2	`319-2`	SSCG_00146	M2	319-1;L-cysteine from: 319-1	`NC(CCCC(NC(C(O)=O)CS)=O)C(O)=O`	—
3	`319-3`	SSCG_00146	M3	319-2;L-Valine from: 319-2	`NC(CCCC(NC(C(N[C@@](C)(C(O)=O)C(C)C)=O)CS)=O)C(O)=O`	—
4	`319-4`	SSCG_00147	—	319-3 from: 319-3	`NC(CCCC(NC1C2SC(C)(C)[C@](C)(C(O)=O)N2C1=O)=O)C(O)=O`	—
5	`319-5`	SSCG_00135	—	319-4 from: 319-4	`NC(CCCC(NC1C2SC(C)(C)[C@](C)(C(O)=O)N2C1=O)=O)C(O)=O`	—
6	`319-6`	SSCG_00134	—	319-5 from: 319-5	`NC(CCCC(NC1[C@@H]2N(C(C(O)=O)=C(C)CS2)C1=O)=O)C(O)=O`	—
7	`319-7`	SSCG_00139	—	319-6 from: 319-6	`NC(CCCC(NC1[C@@H]2N(C(C(O)=O)=C(CO)CS2)C1=O)=O)C(O)=O`	—
8	`319-8`	SSCG_00140	—	319-7 from: 319-7	`NC(CCCC(NC1[C@@H]2N(C(C(O)=O)=C(COC(N)=O)CS2)C1=O)=O)C(O)=O`	—
9	`319`	SSCG_00137,SSCG_00128	—	319-8 from: 319-8	`NC(CCCC(N[C@@]1(OC)[C@@H]2N(C(C(O)=O)=C(COC(N)=O)CS2)C1=O)=O)C(O)=O`	—

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