NPdia

BGC0000171PKS

9-Methylstreptimidone

Producing organism: Streptomyces himastatinicus ATCC 53653
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces›Streptomyces violaceusniger group
Biosynthetic class: PKS (Type I)
Total steps: 8
DOI: 10.1021/ol400224n
MIBiG entry: View on MIBiG ↗

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9-methylstreptimidone

C₁₇H₂₅NO₄307.18 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Unknown

Domains

Ketosynthase (KS)

Acyltransferase (AT)

Ketoreductase (KR)

Acyl carrier protein (ACP)

Acyl carrier (ACP)

Adenylation (A)

Acyl carrier (ACP)

Thioesterase (TE)

Trans-AT docking

Dehydratase (DH2)

Dehydratase (DHt)

Methyltransferase

8 steps · 7 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`171-1`	smdG;smdH	Loading		`O=C(O)CC(O)=O`	—
2	`171-2`	smdI	M1	171-1 from: 171-1	`O=C(N)C/C=C/C(O)=O`	{'transAT': ['smdF', 'Malony…
3	`171-3`	smdI	M2	171-2 from: 171-2	`O=C(N1)CC(CC(O)=O)CC1=O`	{'transAT': ['smdF', 'Malony…
4	`171-4`	smdI	M3	171-3 from: 171-3	`C=C(N1)CC(C[C@@H](O)CC(O)=O)CC1=O`	{'transAT': ['smdF', 'Malony…
5	`171-5`	smdI	M4	171-4 from: 171-4	`O=C(N1)CC(C[C@@H](O)CC([C@H](C(O)=O)C)=O)CC1=O`	{'transAT': ['smdF', 'Malony…
6	`171-6`	smdI	M5	171-5 from: 171-5	`O=C(N1)CC(C[C@@H](O)CC([C@H](/C=C(/C=C(C(O)=O)\C)C)C)=O)CC1=O`	{'transAT': ['smdF', 'Malony…
7	`171-7`	smdE	—	171-6 from: 171-6	`O=C(N1)CC(C[C@@H](O)CC([C@H](/C=C(/C=C(C(O)=O)\C)C)C)=O)CC1=O`	—
8	`171`	smdK	—	171-7 from: 171-7	`O=C(N1)CC(C[C@@H](O)CC([C@H](/C=C(/C=C\C)C)C)=O)CC1=O`	—

Click any row to view the chemical structure · Click a module badge (M1, TE…) to view domain architecture