NPdia

BGC0000123PKS

phoslactomycin B

Producing organism: Streptomyces sp. HK803
Taxonomy: Bacteria›Actinomycetota›Actinomycetes›Kitasatosporales›Streptomycetaceae›Streptomyces
Biosynthetic class: PKS (Unknown)
Total steps: 10
DOI: 10.1074/jbc.M305082200
MIBiG entry: View on MIBiG ↗

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phoslactomycin B

C₂₅H₄₀NO₈P513.25 Da

Biosynthetic (core)

Biosynthetic (additional)

Regulatory

Transport

Other

Unknown

Domains

Ketosynthase (KS)

Acyltransferase (AT)

Dehydratase (DH)

Enoylreductase (ER)

Ketoreductase (KR)

Acyl carrier protein (ACP)

Acyl carrier (ACP)

Adenylation (A)

Thioesterase (TE)

Docking N-term

Docking C-term

Aminotransferase I/II

10 steps · 9 edges

Starting stepIntermediateFinal product│ModuleLoadingTENo module│PKS stepNRPS stepTailoring/otherScroll to pan · Wheel to zoom

Biosynthetic Reactions10 steps

Step	Product ID	Enzyme	Module	Substrate	Product SMILES	Notes
1	`123-1`	plm1	—	Cyclohexanecarboxylic acid	`O=C(O)C1CCCCC1`	—
2	`123-2`	plm1	—	Malonyl-CoA;123-1 from: 123-1	`OC(/C=C\C1CCCCC1)=O`	—
3	`123-3`	plm2-3	—	Malonyl-CoA;123-2 from: 123-2	`OC(/C=C\C=C/C1CCCCC1)=O`	—
4	`123-4`	plm2-3	—	Malonyl-CoA;123-3 from: 123-3	`O[C@H](CC(O)=O)/C=C\C=C/C1CCCCC1`	—
5	`123-5`	plm4	—	Ethylmalonyl-CoA;123-4 from: 123-4	`O[C@H](C[C@@H](O)[C@H](C(O)=O)CC)/C=C\C=C/C1CCCCC1`	—
6	`123-6`	plm5	—	Malonyl-CoA;123-5 from: 123-5	`O[C@H](C[C@@H](O)[C@H](/C=C/C(O)=O)CC)/C=C\C=C/C1CCCCC1`	—
7	`123-7`	plm6	—	Ethylmalonyl-CoA;123-6 from: 123-6	`O[C@H](C[C@@H](O)[C@H](/C=C/[C@H](O)[C@H](C(O)=O)CC)CC)/C=C\C=C/C1CCCCC1`	—
8	`123-8`	plm7	—	Malonyl-CoA;123-7 from: 123-7	`O[C@H](C[C@@H](O)[C@H](/C=C/[C@H](O)[C@H](C(O)CC(O)=O)CC)CC)/C=C\C=C/C1CCCCC1`	—
9	`123-9`	plm7	—	123-8 from: 123-8	`O[C@H](C[C@@H](O)[C@H](/C=C/[C@H]1[C@@H](CC)[C@H](O)CC(O1)=O)CC)/C=C\C=C/C2CCCCC2`	—
10	`123`	?	—	123-9 from: 123-9	`O[C@H](C[C@@H](OP(O)(O)=O)[C@](CCN)(O)/C=C/[C@H]1[C@@H](CC)C=CC(O1)=O)/C=C\C=C/C2CC([H])CCC2`	—

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